Research - The way Celiac Disease is diagnosed is not monolithic

Celiac Disease (CD) is notoriously difficult to diagnose, even in the best case scenario.  Today's featured scientific article is about a man whose only sign of CD was inflammation called "polyserositis" affecting, heart, lungs and brain.  It's unclear why they did an endoscopy in that case, but they did, and it revealed the CD.  Technically, other things can cause jejunal lining destruction.  So I'm a bit doubtful about the last few sentences.  They say the man's outcome  was that he had partial recovery from CD because it was hard for him to avoid all gluten (that's probably true, I've heard the same in other research from Tunisia).  But there is more to that story, I'm sure.

 In any case, it helps to know that the way CD is diagnosed is not monolithic.  

[Celiac disease in adult patients revealed by polyserositis: about a case].


Celiac disease (CD) is an autoimmune disease affecting multiple organs. It often presents as gastrointestinal manifestations associated with malabsorption. However, serosa involvement uncommonly reveals this enteropathy, making the diagnosis difficult. We here report the case of JA, aged 63 years, admitted to hospital to detect the cause of malabsorption syndrome associated with polyserositis signs including pleurisy, pericarditis, ascites and hydrocephalus. The diagnosis of CD was based on endoscopic signs without serology tests. Patient's evolution was partially favorable, due to lack of compliance with a gluten-free diet. Our study reports the first case of CD revealed by polyserositis. CD should be suspected in patients with malabsorption syndrome, in the absence of evocative signs.

Disclaimer: I am not a doctor or a scientist.  I'm a blogger.  If you have health questions, you should consider all sources of information, including your doctor, and you shouldn't change things unless you have good reasons to do so and have discussed them with a trained medical professional.  In my experience, the best doctors will react with interest when you bring them information like freshly published studies.  But I should warn you that some MD's may react with scorn.  My health outcomes have been much better since my doctor and I have been researching my condition, but your results may not match mine.


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